Thorne

Vitamin D/K2 (D-10,000 + K2 or D/K2 Liquid)

68/100

70.2% positive · 23.6% negative · 161 relevant Reddit texts analyzed · updated 2026-08-24

What Reddit Says

Positive
70.2%
Neutral
6.2%
Negative
23.6%

By topic

stress mood74% positive38 mentions
quality trust87% positive38 mentions
energy70% positive37 mentions
side effects56% positive36 mentions
sleep81% positive31 mentions
effectiveness92% positive25 mentions
value86% positive22 mentions
Read what users actually said

Positive experiences

  • “sun exposure for vitamin D is actually pretty effective when done right, but the variables matter a lot. midday sun (10am-2pm) is when UVB rays are strongest, and you want direct skin exposure, meaning arms, legs, and chest if possible,...”
  • “It sounds like you’re doing a lot of good research. If you have time and inclination you can start by eating more iron containing foods like meat. That would also supply you with small amounts of vitamin k2. If cheese is your thing hard...”
  • “I’m actually a little concerned nobody in this thread is talking about the real issue here which is that this stack is, and I say this with love, kind of bare. NMN at 20? Fine I guess, but you’re leaving serious NAD+ flux on the table....”
  • “These are all simple fixes. D3/k2, iron bisglycinate, and a b complex will fix the levels. I'd get NOW for the d3/k2 (5k iu a day) and iron. Don't need anything fancy for those. Thorne is good for the b complex since it uses high...”

Critical experiences

  • “I am 22 and have fibromyalgia (mostly showing up as fatigue, brain fog/memory issues, muscle/body aches, etc.), have ADHD, depression/anxiety. I also have Binocular Vision Dysfunction (eye problems). I have a family history of heart...”
  • “Vitamin K is made in the colon. A healthy gut converts K to K2. If someone has a healthy gut (or taking a good probiotic), a teaspoon of kale is enough K1 to covert to K2. So I'm gonna try the non-suppplemental K2 route and see how it...”
  • “\\\\\\Previous post-\\\\\\ Brain fog, anxiety, breathlessness I was doing good but somehow I am not now. I wanted to treat my anxiety, my constant fatique and brain fog so I have been taking the following supplements for...”

How It Works

Vitamin D3 is not just a vitamin, it is a secosteroid hormone precursor. Once converted by liver and kidneys to calcitriol, it binds the VDR nuclear receptor and tunes expression of hundreds of genes, including antimicrobial peptides central to immune defense and genes governing calcium absorption. K2 (MK-4/MK-7) activates matrix GLA protein and osteocalcin, proteins that direct absorbed calcium into bone instead of arteries. The combo exists because D3 raises calcium absorption while K2 routes it, which is why practitioners pair them.

Key Functions It Supports

  • immune support
  • bone health
  • hormones

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